Strixhaven: School of Mages is a bottom-up enemy color faction set based on “instants and spells matter”. Creatively, the design of this set is Magic’s take on the magical school genre. Each one of the featured colleges represents one of Magic’s enemy color combinations, with their own character and mechanics. Cards associated with the different colleges feature separate watermarked insignias. This set contains 275 regular cards and includes randomly inserted premium versions of all cards.
This set introduces the term mana value as a wording change for converted mana cost. Also, "shuffle your library" is shortened to shuffle and "activate this ability only any time you could cast a sorcery" is shortened to "activate only as a sorcery."